A new in vivo analysis model to detect sexually dimorphic rat liver cytochrome P450 gene expression dependent on growth hormone secretory patterns

Several drug-metabolizing cytochrome P450 (CYP) enzymes exhibit sexual dimorphism depending on the pituitary growth hormone (GH) secretory patterns. However, the mechanism underlying CYP sexual dimorphism remains unclear. We previously established a transgenic (Alb-DsRed2 Tg) rat that expressed red...

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Detalles Bibliográficos
Autores principales: Maruyama, Motoyo, Fujisawa, Masahiko, Yokosuka, Makoto, Saito, Toru R., Hayama, Shin-ichi, Akimoto, Toshio, Hakamata, Yoji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2016
Materias:
Original
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5111848/
https://www.ncbi.nlm.nih.gov/pubmed/27356855
http://dx.doi.org/10.1538/expanim.16-0030

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