Extracellular Antibody Drug Conjugates Exploiting the Proximity of Two Proteins

The human Na(+)/K(+)-ATPase (NKA) is a plasma membrane ion pump that uses ATP to help maintain the resting potential of all human cells. Inhibition of the NKA leads to cell swelling and death. The results of this investigation show that on cancer cells, the NKA either comes in close proximity to, as...

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Detalles Bibliográficos
Autores principales: Marshall, David J, Harried, Scott S, Murphy, John L, Hall, Chad A, Shekhani, Mohammed S, Pain, Christophe, Lyons, Conner A, Chillemi, Antonella, Malavasi, Fabio, Pearce, Homer L, Thorson, Jon S, Prudent, James R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112037/
https://www.ncbi.nlm.nih.gov/pubmed/27434591
http://dx.doi.org/10.1038/mt.2016.119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112037/
https://www.ncbi.nlm.nih.gov/pubmed/27434591
http://dx.doi.org/10.1038/mt.2016.119

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