Enhancing Virion Tethering by BST2 Sensitizes Productively and Latently HIV-infected T cells to ADCC Mediated by Broadly Neutralizing Antibodies

Binding of anti-HIV antibodies (Abs) to envelope (Env) glycoproteins on infected cells can mark them for elimination via antibody-dependent cell-mediated cytotoxicity (ADCC). BST2, a type I interferon (IFN)-stimulated restriction factor that anchors nascent Env-containing virions at the surface of i...

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Detalles Bibliográficos
Autores principales: Pham, Tram N. Q., Lukhele, Sabelo, Dallaire, Frédéric, Perron, Gabrielle, Cohen, Éric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112552/
https://www.ncbi.nlm.nih.gov/pubmed/27853288
http://dx.doi.org/10.1038/srep37225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112552/
https://www.ncbi.nlm.nih.gov/pubmed/27853288
http://dx.doi.org/10.1038/srep37225

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