Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy

Tropomyosin receptor kinase C (TrkC) targeted ligand-photosensitizer construct, IYIY-diiodo-boron-dipyrromethene (IYIY-I(2)-BODIPY) and its scrambled counterpart YIYI-I(2)-BODIPY have been prepared. IYIY-I(2)-BODIPY binds TrkC similar to neurotrophin-3 (NT-3), and NT-3 has been reported to modulate...

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Detalles Bibliográficos
Autores principales: Kue, Chin Siang, Kamkaew, Anyanee, Voon, Siew Hui, Kiew, Lik Voon, Chung, Lip Yong, Burgess, Kevin, Lee, Hong Boon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112560/
https://www.ncbi.nlm.nih.gov/pubmed/27853305
http://dx.doi.org/10.1038/srep37209

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112560/
https://www.ncbi.nlm.nih.gov/pubmed/27853305
http://dx.doi.org/10.1038/srep37209

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