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Tropomyosin Receptor Kinase C Targeted Delivery of a Peptidomimetic Ligand-Photosensitizer Conjugate Induces Antitumor Immune Responses Following Photodynamic Therapy
Tropomyosin receptor kinase C (TrkC) targeted ligand-photosensitizer construct, IYIY-diiodo-boron-dipyrromethene (IYIY-I(2)-BODIPY) and its scrambled counterpart YIYI-I(2)-BODIPY have been prepared. IYIY-I(2)-BODIPY binds TrkC similar to neurotrophin-3 (NT-3), and NT-3 has been reported to modulate...
Autores principales: | Kue, Chin Siang, Kamkaew, Anyanee, Voon, Siew Hui, Kiew, Lik Voon, Chung, Lip Yong, Burgess, Kevin, Lee, Hong Boon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112560/ https://www.ncbi.nlm.nih.gov/pubmed/27853305 http://dx.doi.org/10.1038/srep37209 |
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