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OSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis
We investigated the role of oxidative stress-responsive kinase-1 (OSR1) and STE20 (sterile 20)/SPS1-related proline/alanine-rich kinase (SPAK), upstream regulators of the Na(+)-K(+)-2Cl(−) cotransporter (NKCC1)—essential for spermatogenesis—in mouse models of male fertility. Global OSR1(+/−) gene mu...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112561/ https://www.ncbi.nlm.nih.gov/pubmed/27853306 http://dx.doi.org/10.1038/srep37205 |