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OSR1 and SPAK cooperatively modulate Sertoli cell support of mouse spermatogenesis

We investigated the role of oxidative stress-responsive kinase-1 (OSR1) and STE20 (sterile 20)/SPS1-related proline/alanine-rich kinase (SPAK), upstream regulators of the Na(+)-K(+)-2Cl(−) cotransporter (NKCC1)—essential for spermatogenesis—in mouse models of male fertility. Global OSR1(+/−) gene mu...

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Detalles Bibliográficos
Autores principales:	Liu, Yung-Liang, Yang, Sung-Sen, Chen, Shyi-Jou, Lin, Yu-Chun, Chu, Chin-Chen, Huang, Hsin-Hui, Chang, Fung-Wei, Yu, Mu-Hsien, Lin, Shih-Hua, Wu, Gwo-Jang, Sytwu, Huey-Kang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112561/ https://www.ncbi.nlm.nih.gov/pubmed/27853306 http://dx.doi.org/10.1038/srep37205

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