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Regulation of Sirt1/Nrf2/TNF-α signaling pathway by luteolin is critical to attenuate acute mercuric chloride exposure induced hepatotoxicity

Inorganic mercury, though a key component of pediatric vaccines, is an environmental toxicant threatening human health via accumulating oxidative stress in part. Luteolin has been of great interest because of its antiinflammatory, anticarcinogenic and antioxidative effects. Here we hypothesized that...

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Detalles Bibliográficos
Autores principales: Yang, Daqian, Tan, Xiao, Lv, Zhanjun, Liu, Biying, Baiyun, Ruiqi, Lu, Jingjing, Zhang, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112569/
https://www.ncbi.nlm.nih.gov/pubmed/27853236
http://dx.doi.org/10.1038/srep37157