Exosomes derived from embryonal and alveolar rhabdomyosarcoma carry differential miRNA cargo and promote invasion of recipient fibroblasts

Rhabdomyosarcoma (RMS) is an aggressive childhood soft tissue tumor, which exists in oncoprotein PAX-FOXO1 fusion positive and fusion negative subtypes, with the fusion-positive RMS being characterized by a more aggressive clinical behavior. Exosomes are small membranous vesicles secreted into body...

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Detalles Bibliográficos
Autores principales: Ghayad, Sandra E., Rammal, Ghina, Ghamloush, Farah, Basma, Hussein, Nasr, Rihab, Diab-Assaf, Mona, Chelala, Claude, Saab, Raya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112573/
https://www.ncbi.nlm.nih.gov/pubmed/27853183
http://dx.doi.org/10.1038/srep37088

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