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Imprinting of cerebral cytochrome P450s in offsprings prenatally exposed to cypermethrin augments toxicity on rechallenge

Epigenetic studies were carried in the rat offsprings, born to dams treated with cypermethrin (orally; 5.0 mg/kg) from gestation day (GD) 5 to 21 and rechallenged with cypermethrin (orally; 10 mg/kg for 6 days), at adulthood (12 weeks) to understand the mechanism underlying the overexpression of cer...

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Detalles Bibliográficos
Autores principales: Singh, Anshuman, Agrahari, Anita, Singh, RadhaDutt, Yadav, Sanjay, Srivastava, Vikas, Parmar, Devendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112598/
https://www.ncbi.nlm.nih.gov/pubmed/27853314
http://dx.doi.org/10.1038/srep37426

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