Pyroptosis of Salmonella Typhimurium-infected macrophages was suppressed and elimination of intracellular bacteria from macrophages was promoted by blocking QseC

QseC is a membrane-bound histidine sensor kinase found in Gram-negative pathogens and is involved in the regulation of bacterial virulence. LED209, a QseC-specific inhibitor, significantly inhibits the virulence of several pathogens and partially protects infected mice from death by blocking QseC. H...

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Detalles Bibliográficos
Autores principales: Li, Zhi, Zheng, Qing, Xue, Xiaoyan, Shi, Xin, Zhou, Ying, Da, Fei, Qu, Di, Hou, Zheng, Luo, Xiaoxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112599/
https://www.ncbi.nlm.nih.gov/pubmed/27853287
http://dx.doi.org/10.1038/srep37447

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112599/
https://www.ncbi.nlm.nih.gov/pubmed/27853287
http://dx.doi.org/10.1038/srep37447

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