Cargando…

Schisandra polysaccharide inhibits hepatic lipid accumulation by downregulating expression of SREBPs in NAFLD mice

BACKGROUND: Hepatoprotective effects of Chinese herbal medicine Schisandra Chinensis (Schisandra) have been widely investigated. However, most studies were focused on its lignan extracts. We investigated the effects of Schisandra polysaccharide (SCP) in a mouse model of non-alcoholic fatty liver dis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Chun-Mei, Yuan, Rong-Shuang, Zhuang, Wen-Yue, Sun, Jing-Hui, Wu, Jin-Ying, Li, He, Chen, Jian-Guang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112637/ https://www.ncbi.nlm.nih.gov/pubmed/27852305 http://dx.doi.org/10.1186/s12944-016-0358-5

Ejemplares similares

Xyloketal B Attenuates Fatty Acid-Induced Lipid Accumulation via the SREBP-1c Pathway in NAFLD Models
por: Zhang, Youying, et al.
Publicado: (2017)

Immunomodulatory effect of Schisandra polysaccharides in cyclophosphamide-induced immunocompromised mice
por: Yu, Jiahui, et al.
Publicado: (2018)

Rhinacanthin C Ameliorates Insulin Resistance and Lipid Accumulation in NAFLD Mice via the AMPK/SIRT1 and SREBP-1c/FAS/ACC Signaling Pathways
por: Gong, Zhiqiang, et al.
Publicado: (2023)

Loss of hepatic FTCD promotes lipid accumulation and hepatocarcinogenesis by upregulating PPARγ and SREBP2
por: Wang, Siying, et al.
Publicado: (2023)

Effects of Schisandra chinensis Polysaccharide-Conjugated Selenium Nanoparticles on Intestinal Injury in Mice
por: Du, Hongxu, et al.
Publicado: (2023)

Effects of Selenylation Modification on Antioxidative Activities of Schisandra chinensis Polysaccharide
por: Yue, Chanjuan, et al.
Publicado: (2015)

Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans
por: Hendrix, Sebastian, et al.
Publicado: (2023)

TAK1 regulates hepatic lipid homeostasis through SREBP
por: Morioka, Sho, et al.
Publicado: (2016)

Obesity-Induced Upregulation of ZBTB7A Promotes Lipid Accumulation through SREBP1
por: Zhou, Jing-ping, et al.
Publicado: (2020)

Dendrobium officinale Regulates Fatty Acid Metabolism to Ameliorate Liver Lipid Accumulation in NAFLD Mice
por: Lei, Shan-Shan, et al.
Publicado: (2021)

Magma Seawater Inhibits Hepatic Lipid Accumulation through Suppression of Lipogenic Enzymes Regulated by SREBPs in Thioacetamide-Injected Rats
por: Woo, Minji, et al.
Publicado: (2019)

The LATS2 tumor suppressor inhibits SREBP and suppresses hepatic cholesterol accumulation
por: Aylon, Yael, et al.
Publicado: (2016)

Metabolomics study of the therapeutic mechanism of Schisandra Chinensis lignans in diet-induced hyperlipidemia mice
por: Sun, Jing-Hui, et al.
Publicado: (2017)

Dietary Fructus Schisandrae extracts and fenofibrate regulate the serum/hepatic lipid-profile in normal and hypercholesterolemic mice, with attention to hepatotoxicity
por: Pan, Si-Yuan, et al.
Publicado: (2012)

Hepatic G Protein-Coupled Receptor 180 Deficiency Ameliorates High Fat Diet-Induced Lipid Accumulation via the Gi-PKA-SREBP Pathway
por: Zhang, Yunhua, et al.
Publicado: (2023)

Tanshinone IIA Downregulates Lipogenic Gene Expression and Attenuates Lipid Accumulation through the Modulation of LXRα/SREBP1 Pathway in HepG2 Cells
por: Gao, Wan-Yun, et al.
Publicado: (2021)

Impaired Hepatic Vitamin A Metabolism in NAFLD Mice Leading to Vitamin A Accumulation in Hepatocytes
por: Saeed, Ali, et al.
Publicado: (2020)

Schisandra chinensis (Turcz.) Baill. polysaccharide inhibits influenza A virus in vitro and in vivo
por: Qi, Jing, et al.
Publicado: (2023)

SREBP activation contributes to fatty acid accumulations in necroptosis
por: Lu, Daniel, et al.
Publicado: (2023)

Intestinal Microbiota Contributes to the Improvement of Alcoholic Hepatitis in Mice Treated With Schisandra chinensis Extract
por: Xiang, Jun-Yan, et al.
Publicado: (2022)

Gemfibrozil reduces lipid accumulation in SMMC-7721 cells via the involvement of PPARα and SREBP1
por: Zhang, Xiaonan, et al.
Publicado: (2019)

The Anti-colitis Effect of Schisandra chinensis Polysaccharide Is Associated With the Regulation of the Composition and Metabolism of Gut Microbiota
por: Su, Lianlin, et al.
Publicado: (2020)

Increased LDL receptor by SREBP2 or SREBP2-induced lncRNA LDLR-AS promotes triglyceride accumulation in fish
por: Cao, Xiufei, et al.
Publicado: (2022)

Bile salt hydrolase-overexpressing Lactobacillus strains can improve hepatic lipid accumulation in vitro in an NAFLD cell model
por: Huang, Wenli, et al.
Publicado: (2020)

Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation
por: Latorre, Jessica, et al.
Publicado: (2022)

A Nutraceutical Formulation Containing Brown Algae Reduces Hepatic Lipid Accumulation by Modulating Lipid Metabolism and Inflammation in Experimental Models of NAFLD and NASH
por: Gabbia, Daniela, et al.
Publicado: (2022)

Electromagnetic fields ameliorate hepatic lipid accumulation and oxidative stress: potential role of CaMKKβ/AMPK/SREBP-1c and Nrf2 pathways
por: Zhai, Mingming, et al.
Publicado: (2023)

Study on the Hepatoprotection of Schisandra chinensis Caulis Polysaccharides in Nonalcoholic Fatty Liver Disease in Rats Based on Metabolomics
por: Feng, Yanbo, et al.
Publicado: (2021)

N-Acetyl Cysteine Targets Hepatic Lipid Accumulation to Curb Oxidative Stress and Inflammation in NAFLD: A Comprehensive Analysis of the Literature
por: Dludla, Phiwayinkosi V., et al.
Publicado: (2020)

Hepatic triglyceride accumulation via endoplasmic reticulum stress-induced SREBP-1 activation is regulated by ceramide synthases
por: Kim, Ye-Ryung, et al.
Publicado: (2019)

Expression of SREBP-1c Requires SREBP-2-mediated Generation of a Sterol Ligand for LXR in Livers of Mice
por: Rong, Shunxing, et al.
Publicado: (2017)

EZH2 Down-Regulation Exacerbates Lipid Accumulation and Inflammation in in Vitro and in Vivo NAFLD
por: Vella, Serena, et al.
Publicado: (2013)

MD2 AMP(K)s up the link between lipid accumulation and inflammation in NAFLD
por: Heldens, Anneleen, et al.
Publicado: (2022)

Effect of Fructus schisandrae syrup on bronchial asthma mice model
por: Peng, Mengfan, et al.
Publicado: (2018)

Targeted Lignan Profiling and Anti-Inflammatory Properties of Schisandra rubriflora and Schisandra chinensis Extracts
por: Szopa, Agnieszka, et al.
Publicado: (2018)

Schisandra Fruit Vinegar Lowers Lipid Profile in High-Fat Diet Rats
por: Yuan, Rui, et al.
Publicado: (2020)

Dietary pulp from Fructus Schisandra Chinensis supplementation reduces serum/hepatic lipid and hepatic glucose levels in mice fed a normal or high cholesterol/bile salt diet
por: Sun, Nan, et al.
Publicado: (2014)

Alternate Ultrasound/Microwave Digestion for Deep Eutectic Hydro-distillation Extraction of Essential Oil and Polysaccharide from Schisandra chinensis (Turcz.) Baill
por: Li, Jun-Han, et al.
Publicado: (2019)

Impact of silencing hepatic SREBP-1 on insulin signaling
por: Jideonwo, Victoria, et al.
Publicado: (2018)

The SCAP/SREBP Pathway: A Mediator of Hepatic Steatosis
por: Moon, Young-Ah
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_37bkp9mdf0d3e9pkcbgoeppgvh