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MicroRNA-29 facilitates transplantation of bone marrow-derived mesenchymal stem cells to alleviate pelvic floor dysfunction by repressing elastin

BACKGROUND: Pelvic floor dysfunction (PFD) is a condition affecting many women worldwide, with symptoms including stress urinary incontinence (SUI) and pelvic organ prolapse (POP). We have previously demonstrated stable elastin-expressing bone marrow-derived mesenchymal stem cells (BMSCs) attenuated...

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Detalles Bibliográficos
Autores principales: Jin, Minfei, Wu, Yuelin, Wang, Jun, Ye, Weiping, Wang, Lei, Yin, Peipei, Liu, Wei, Pan, Chenhao, Hua, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112649/
https://www.ncbi.nlm.nih.gov/pubmed/27855713
http://dx.doi.org/10.1186/s13287-016-0428-7