Coevolution of paired receptors in Xenopus carcinoembryonic antigen-related cell adhesion molecule families suggests appropriation as pathogen receptors

BACKGROUND: In mammals, CEACAM1 and closely related members represent paired receptors with similar extracellular ligand-binding regions and cytoplasmic domains with opposing functions. Human CEACAM1 and CEACAM3 which have inhibitory ITIM/ITSM and activating ITAM-like motifs, respectively, in their...

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Detalles Bibliográficos
Autores principales: Zimmermann, Wolfgang, Kammerer, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112662/
https://www.ncbi.nlm.nih.gov/pubmed/27852220
http://dx.doi.org/10.1186/s12864-016-3279-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112662/
https://www.ncbi.nlm.nih.gov/pubmed/27852220
http://dx.doi.org/10.1186/s12864-016-3279-9

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