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MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancer

BACKGROUND: Cancer cells exhibit an altered metabolism, which is characterized by a preference for aerobic glycolysis more than mitochondrial oxidation of pyruvate. Mitochondrial pyruvate carrier 1 (MPC1) and mitochondrial pyruvate carrier 2 (MPC2) play a bottleneck role by transporting pyruvate int...

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Detalles Bibliográficos
Autores principales:	Li, Xiaoli, Ji, Yasai, Han, Gaoyang, Li, Xiaoran, Fan, Zhirui, Li, Yaqing, Zhong, Yali, Cao, Jing, Zhao, Jing, Zhang, Mingzhi, Wen, Jianguo, Goscinski, Mariusz Adam, Nesland, Jahn M., Suo, Zhenhe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112705/ https://www.ncbi.nlm.nih.gov/pubmed/27852261 http://dx.doi.org/10.1186/s12885-016-2941-6

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