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Long-lasting reduction in clonogenic potential of colorectal cancer cells by sequential treatments with 5-azanucleosides and topoisomerase inhibitors

BACKGROUND: The currently approved therapies fail in a substantial number of colorectal cancer (CRC) patients due to the molecular heterogeneity of CRC, hence new efficient drug combinations are urgently needed. Emerging data indicate that 5-azanucleosides are able to sensitize cancer cells to the s...

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Detalles Bibliográficos
Autores principales:	Pawlak, Alicja, Ziolo, Ewa, Fiedorowicz, Anna, Fidyt, Klaudyna, Strzadala, Leon, Kalas, Wojciech
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112712/ https://www.ncbi.nlm.nih.gov/pubmed/27852227 http://dx.doi.org/10.1186/s12885-016-2925-6

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