Variations in DNA methylation of interferon gamma and programmed death 1 in allograft rejection after kidney transplantation

BACKGROUND: The role of DNA methylation in the regulation of the anti-donor-directed immune response after organ transplantation is unknown. Here, we studied the methylation of two mediators of the immune response: the pro-inflammatory cytokine interferon γ (IFNγ) and the inhibitory receptor program...

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Detalles Bibliográficos
Autores principales: Boer, Karin, de Wit, L. Elly A., Peters, Fleur S., Hesselink, Dennis A., Hofland, Leo J., Betjes, Michiel G. H., Looman, Caspar W. N., Baan, Carla C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112717/
https://www.ncbi.nlm.nih.gov/pubmed/27891189
http://dx.doi.org/10.1186/s13148-016-0288-0

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