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Impaired anti-inflammatory action of glucocorticoid in neutrophil from patients with steroid-resistant asthma
BACKGROUND: Steroid resistant (SR) asthma is characterized by persistent airway inflammation that fails to resolve despite treatment with high doses of corticosteroids. Furthermore, SR patient airways show increased numbers neutrophils, which are less responsive to glucocorticoid. The present study...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112750/ https://www.ncbi.nlm.nih.gov/pubmed/27852250 http://dx.doi.org/10.1186/s12931-016-0462-0 |