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Impaired anti-inflammatory action of glucocorticoid in neutrophil from patients with steroid-resistant asthma

BACKGROUND: Steroid resistant (SR) asthma is characterized by persistent airway inflammation that fails to resolve despite treatment with high doses of corticosteroids. Furthermore, SR patient airways show increased numbers neutrophils, which are less responsive to glucocorticoid. The present study...

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Detalles Bibliográficos
Autores principales: Wang, Meijia, Gao, Pengfei, Wu, Xiaojie, Chen, Yuetao, Feng, Yikuan, Yang, Qun, Xu, Yongjian, Zhao, Jianping, Xie, Jungang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112750/
https://www.ncbi.nlm.nih.gov/pubmed/27852250
http://dx.doi.org/10.1186/s12931-016-0462-0