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Tumor-Activated Mesenchymal Stromal Cells Promote Osteosarcoma Stemness and Migratory Potential via IL-6 Secretion

Osteosarcoma (OS) is an aggressive bone malignancy with a high relapse rate despite combined treatment with surgery and multiagent chemotherapy. As for other cancers, OS-associated microenvironment may contribute to tumor initiation, growth, and metastasis. We consider mesenchymal stromal cells (MSC...

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Detalles Bibliográficos
Autores principales:	Cortini, Margherita, Massa, Annamaria, Avnet, Sofia, Bonuccelli, Gloria, Baldini, Nicola
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112800/ https://www.ncbi.nlm.nih.gov/pubmed/27851822 http://dx.doi.org/10.1371/journal.pone.0166500

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