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PLD-Specific Small-Molecule Inhibitors Decrease Tumor-Associated Macrophages and Neutrophils Infiltration in Breast Tumors and Lung and Liver Metastases

Phospholipase D-2 (PLD2) has a key role in breast cancer formation and metastasis formation with PLD small inhibitors reducing primary tumor growth. This study aimed to evaluate the importance of targeting PLD on the tumor microenvironment. We provide evidence about the beneficial effect of PLD inhi...

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Detalles Bibliográficos
Autores principales:	Henkels, Karen M., Muppani, Naveen Reddy, Gomez-Cambronero, Julian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112812/ https://www.ncbi.nlm.nih.gov/pubmed/27851813 http://dx.doi.org/10.1371/journal.pone.0166553

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