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Lactate Inhibits the Pro-Inflammatory Response and Metabolic Reprogramming in Murine Macrophages in a GPR81-Independent Manner

Lactate is an essential component of carbon metabolism in mammals. Recently, lactate was shown to signal through the G protein coupled receptor 81 (GPR81) and to thus modulate inflammatory processes. This study demonstrates that lactate inhibits pro-inflammatory signaling in a GPR81-independent fash...

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Detalles Bibliográficos
Autores principales:	Errea, Agustina, Cayet, Delphine, Marchetti, Philippe, Tang, Cong, Kluza, Jerome, Offermanns, Stefan, Sirard, Jean-Claude, Rumbo, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112849/ https://www.ncbi.nlm.nih.gov/pubmed/27846210 http://dx.doi.org/10.1371/journal.pone.0163694

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