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Trimetazidine attenuates pressure overload-induced early cardiac energy dysfunction via regulation of neuropeptide Y system in a rat model of abdominal aortic constriction

BACKGROUND: Metabolism remodeling has been recognized as an early event following cardiac pressure overload. However, its temporal association with ventricular hypertrophy has not been confirmed. Moreover, whether trimetazidine could favorably affect this process also needs to be determined. The aim...

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Detalles Bibliográficos
Autores principales: Chen, Ailan, Li, Wanglin, Chen, Xinyu, Shen, Yuechun, Dai, Wenjun, Dong, Qi, Li, Xinchun, Ou, Caiwen, Chen, Minsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112876/
https://www.ncbi.nlm.nih.gov/pubmed/27855650
http://dx.doi.org/10.1186/s12872-016-0399-8