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Trimetazidine attenuates pressure overload-induced early cardiac energy dysfunction via regulation of neuropeptide Y system in a rat model of abdominal aortic constriction
BACKGROUND: Metabolism remodeling has been recognized as an early event following cardiac pressure overload. However, its temporal association with ventricular hypertrophy has not been confirmed. Moreover, whether trimetazidine could favorably affect this process also needs to be determined. The aim...
Autores principales: | Chen, Ailan, Li, Wanglin, Chen, Xinyu, Shen, Yuechun, Dai, Wenjun, Dong, Qi, Li, Xinchun, Ou, Caiwen, Chen, Minsheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112876/ https://www.ncbi.nlm.nih.gov/pubmed/27855650 http://dx.doi.org/10.1186/s12872-016-0399-8 |
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