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Human class I major histocompatibility complex alleles determine central nervous system injury versus repair

BACKGROUND: We investigated the role of human HLA class I molecules in persistent central nervous system (CNS) injury versus repair following virus infection of the CNS. METHODS: Human class I A11(+) and B27(+) transgenic human beta-2 microglobulin positive (Hβ2m(+)) mice of the H-2(b) background we...

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Detalles Bibliográficos
Autores principales: Wootla, Bharath, Denic, Aleksandar, Watzlawik, Jens O., Warrington, Arthur E., Zoecklein, Laurie J., Papke-Norton, Louisa M., David, Chella, Rodriguez, Moses
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112886/
https://www.ncbi.nlm.nih.gov/pubmed/27855706
http://dx.doi.org/10.1186/s12974-016-0759-4