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Chromosomal Instability Estimation Based on Next Generation Sequencing and Single Cell Genome Wide Copy Number Variation Analysis

Genomic instability is a hallmark of cancer often associated with poor patient outcome and resistance to targeted therapy. Assessment of genomic instability in bulk tumor or biopsy can be complicated due to sample availability, surrounding tissue contamination, or tumor heterogeneity. The Epic Scien...

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Detalles Bibliográficos
Autores principales:	Greene, Stephanie B., Dago, Angel E., Leitz, Laura J., Wang, Yipeng, Lee, Jerry, Werner, Shannon L., Gendreau, Steven, Patel, Premal, Jia, Shidong, Zhang, Liangxuan, Tucker, Eric K., Malchiodi, Michael, Graf, Ryon P., Dittamore, Ryan, Marrinucci, Dena, Landers, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112954/ https://www.ncbi.nlm.nih.gov/pubmed/27851748 http://dx.doi.org/10.1371/journal.pone.0165089

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