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Assessment of Intrathecal Free Light Chain Synthesis: Comparison of Different Quantitative Methods with the Detection of Oligoclonal Free Light Chains by Isoelectric Focusing and Affinity-Mediated Immunoblotting

OBJECTIVES: We aimed to compare various methods for free light chain (fLC) quantitation in cerebrospinal fluid (CSF) and serum and to determine whether quantitative CSF measurements could reliably predict intrathecal fLC synthesis. In addition, we wished to determine the relationship between free ka...

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Detalles Bibliográficos
Autores principales:	Zeman, David, Kušnierová, Pavlína, Švagera, Zdeněk, Všianský, František, Byrtusová, Monika, Hradílek, Pavel, Kurková, Barbora, Zapletalová, Olga, Bartoš, Vladimír
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5112955/ https://www.ncbi.nlm.nih.gov/pubmed/27846293 http://dx.doi.org/10.1371/journal.pone.0166556

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