Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization

Antibodies targeting IL-17A or its receptor IL-17RA show unprecedented efficacy in the treatment of autoimmune diseases such as psoriasis. These therapies, by neutralizing critical mediators of immunity, may increase susceptibility to infections. Here, we compared the effect of antibodies neutralizi...

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Detalles Bibliográficos
Autores principales: Segueni, Noria, Tritto, Elaine, Bourigault, Marie-Laure, Rose, Stéphanie, Erard, François, Le Bert, Marc, Jacobs, Muazzam, Di Padova, Franco, Stiehl, Daniel P., Moulin, Pierre, Brees, Dominique, Chibout, Salah-Dine, Ryffel, Bernhard, Kammüller, Michael, Quesniaux, Valerie F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113257/
https://www.ncbi.nlm.nih.gov/pubmed/27853279
http://dx.doi.org/10.1038/srep36923

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