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The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain

Neuropathic pain results from neuroplasticity in nociceptive neuronal networks. Here we demonstrate that control of alternative pre-mRNA splicing, through the splice factor serine-arginine splice factor 1 (SRSF1), is integral to the processing of nociceptive information in the spinal cord. Neuropath...

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Detalles Bibliográficos
Autores principales: Hulse, Richard P., Drake, Robert A.R., Bates, David O., Donaldson, Lucy F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113660/
https://www.ncbi.nlm.nih.gov/pubmed/27616424
http://dx.doi.org/10.1016/j.nbd.2016.09.009