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Catalytic Enantioselective Synthesis of C (1)‐ and C (2)‐Symmetric Spirobiindanones through Counterion‐Directed Enolate C‐Acylation

A catalytic enantioselective route to C(1)‐ and C(2)‐symmetric 2,2′‐spirobiindanones has been realized through an intramolecular enolate C‐acylation. This reaction employs a chiral ammonium counterion to direct the acylation of an in situ generated ketone enolate with a pentafluorophenyl ester. This...

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Detalles Bibliográficos
Autores principales:	Rahemtulla, Benjamin F., Clark, Hugh F., Smith, Martin D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113699/ https://www.ncbi.nlm.nih.gov/pubmed/27628946 http://dx.doi.org/10.1002/anie.201607731

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