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New Structural Data Reveal the Motion of Carrier Proteins in Nonribosomal Peptide Synthesis
The nonribosomal peptide synthetases (NRPSs) are one of the most promising resources for the production of new bioactive molecules. The mechanism of NRPS catalysis is based around sequential catalytic domains: these are organized into modules, where each module selects, modifies, and incorporates an...
Autores principales: | Kittilä, Tiia, Mollo, Aurelio, Charkoudian, Louise K., Cryle, Max J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113783/ https://www.ncbi.nlm.nih.gov/pubmed/27435901 http://dx.doi.org/10.1002/anie.201602614 |
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