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Trypanosoma brucei CYP51: Essentiality and Targeting Therapy in an Experimental Model
Trypanosoma brucei gambiense is the main causative agent of Human African Trypanosomiasis (HAT), also known as sleeping sickness. Because of limited alternatives and treatment toxicities, new therapeutic options are urgently needed for patients with HAT. Sterol 14alpha-demethylase (CYP51) is a poten...
Autores principales: | Dauchy, Frédéric-Antoine, Bonhivers, Mélanie, Landrein, Nicolas, Dacheux, Denis, Courtois, Pierrette, Lauruol, Florian, Daulouède, Sylvie, Vincendeau, Philippe, Robinson, Derrick R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113867/ https://www.ncbi.nlm.nih.gov/pubmed/27855164 http://dx.doi.org/10.1371/journal.pntd.0005125 |
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