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Double gene siRNA knockdown of mutant p53 and TNF induces apoptosis in triple-negative breast cancer cells

Apoptosis is the major downregulated pathway in cancer. Simultaneous inhibition using specific small interfering RNA (siRNA) of two key player genes, p53 and TNF, is an interesting and feasible strategy when it comes to investigating various molecular pathways and biological processes in triple-nega...

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Detalles Bibliográficos
Autores principales:	Pileczki, Valentina, Pop, Laura, Braicu, Cornelia, Budisan, Livia, Bolba Morar, Gabriela, del C Monroig-Bosque, Paloma, Sandulescu, Robert V, Berindan-Neagoe, Ioana
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113913/ https://www.ncbi.nlm.nih.gov/pubmed/27956838 http://dx.doi.org/10.2147/OTT.S110719

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