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CXCL12 retargeting of an adenovirus vector to cancer cells using a bispecific adapter

Ad vectors are promising delivery vehicles for cancer therapeutic interventions. However, their application is limited by promiscuous tissue tropism and hepatotoxicity. This limitation can be avoided by altering the native tropism of Ads so that they can be redirected to the target cells through alt...

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Detalles Bibliográficos
Autores principales:	Bhatia, Shilpa, O’Bryan, Samia M, Rivera, Angel A, Curiel, David T, Mathis, J Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113939/ https://www.ncbi.nlm.nih.gov/pubmed/27957479 http://dx.doi.org/10.2147/OV.S112107

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