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Cell Transformation by PTP1B Truncated Mutants Found in Human Colon and Thyroid Tumors
Expression of wild-type protein tyrosine phosphatase (PTP) 1B may act either as a tumor suppressor by dysregulation of protein tyrosine kinases or a tumor promoter through Src dephosphorylation at Y527 in human breast cancer cells. To explore whether mutated PTP1B is involved in human carcinogenesis...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113951/ https://www.ncbi.nlm.nih.gov/pubmed/27855221 http://dx.doi.org/10.1371/journal.pone.0166538 |