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Identification and Characterization of a New Protein Isoform of Human 5-Lipoxygenase
Leukotrienes (LTs) are inflammatory mediators that play a pivotal role in many diseases like asthma bronchiale, atherosclerosis and in various types of cancer. The key enzyme for generation of LTs is the 5-lipoxygenase (5-LO). Here, we present a novel putative protein isoform of human 5-LO that lack...
Autores principales: | Häfner, Ann-Kathrin, Beilstein, Kim, Graab, Philipp, Ball, Ann-Katrin, Saul, Meike J., Hofmann, Bettina, Steinhilber, Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113960/ https://www.ncbi.nlm.nih.gov/pubmed/27855198 http://dx.doi.org/10.1371/journal.pone.0166591 |
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