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Characterization of a vraG Mutant in a Genetically Stable Staphylococcus aureus Small-Colony Variant and Preliminary Assessment for Use as a Live-Attenuated Vaccine against Intrammamary Infections
Staphylococcus aureus is a leading cause of bovine intramammary infections (IMIs) that can evolve into difficult-to-treat chronic mastitis. To date, no vaccine formulation has shown high protective efficacy against S. aureus IMI, partly because this bacterium can efficiently evade the immune system....
Autores principales: | Côté-Gravel, Julie, Brouillette, Eric, Obradović, Nataša, Ster, Céline, Talbot, Brian G., Malouin, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113970/ https://www.ncbi.nlm.nih.gov/pubmed/27855187 http://dx.doi.org/10.1371/journal.pone.0166621 |
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