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The Epstein-Barr Virus Immunoevasins BCRF1 and BPLF1 Are Expressed by a Mechanism Independent of the Canonical Late Pre-initiation Complex
Subversion of host immune surveillance is a crucial step in viral pathogenesis. Epstein-Barr virus (EBV) encodes two immune evasion gene products, BCRF1 (viral IL-10) and BPLF1 (deubiquitinase/deneddylase); both proteins suppress antiviral immune responses during primary infection. The BCRF1 and BPL...
Autores principales: | McKenzie, Jessica, Lopez-Giraldez, Francesc, Delecluse, Henri-Jacques, Walsh, Ann, El-Guindy, Ayman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5113994/ https://www.ncbi.nlm.nih.gov/pubmed/27855219 http://dx.doi.org/10.1371/journal.ppat.1006008 |
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