Cargando…

miR-150 Suppresses the Proliferation and Tumorigenicity of Leukemia Stem Cells by Targeting the Nanog Signaling Pathway

Proliferation, a key feature of cancer cells, accounts for the majority of cancer-related diseases resulting in mortality. MicroRNAs (miRNAs) plays important post-transcriptional modulation roles by acting on multiple signaling pathways, but the underlying mechanism in proliferation and tumorigenici...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xu, Dan-dan, Zhou, Peng-jun, Wang, Ying, Zhang, Yi, Zhang, Rong, Zhang, Li, Chen, Su-hong, Fu, Wu-yu, Ruan, Bi-bo, Xu, Hai-peng, Hu, Chao-zhi, Tian, Lu, Qin, Jin-hong, Wang, Sheng, Wang, Xiao, Liu, Qiu-ying, Ren, Zhe, Gu, Xue-kui, Li, Yao-he, Liu, Zhong, Wang, Yi-fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114241/ https://www.ncbi.nlm.nih.gov/pubmed/27917123 http://dx.doi.org/10.3389/fphar.2016.00439

Ejemplares similares

The IGF2/IGF1R/Nanog Signaling Pathway Regulates the Proliferation of Acute Myeloid Leukemia Stem Cells
por: Xu, Dan-dan, et al.
Publicado: (2018)

Suppression of Esophageal Cancer Stem-like Cells by SNX-2112 Is Enhanced by STAT3 Silencing
por: Xu, Dan-dan, et al.
Publicado: (2020)

miR-203 inhibits proliferation and self-renewal of leukemia stem cells by targeting survivin and Bmi-1
por: Zhang, Yi, et al.
Publicado: (2016)

Reciprocal activation between STAT3 and miR-181b regulates the proliferation of esophageal cancer stem-like cells via the CYLD pathway
por: Xu, Dan-dan, et al.
Publicado: (2016)

Soft fibrin matrix downregulates DAB2IP to promote Nanog-dependent growth of colon tumor-repopulating cells
por: Zhang, Meng, et al.
Publicado: (2019)

Non-coding RNAs: The recently accentuated molecules in the regulation of cell autophagy for ovarian cancer pathogenesis and therapeutic response
por: Peng, Bi, et al.
Publicado: (2023)

A Review of Efficacy and Safety of Checkpoint Inhibitor for the Treatment of Acute Myeloid Leukemia
por: Liao, Dan, et al.
Publicado: (2019)

Jiyuan oridonin A induces differentiation of acute myeloid leukemia cells including leukemic stem-like cells
por: Li, Fahui, et al.
Publicado: (2022)

miR-150 inhibits proliferation and tumorigenicity via retarding G1/S phase transition in nasopharyngeal carcinoma
por: Li, Xiangyong, et al.
Publicado: (2017)

A perspective of immunotherapy for acute myeloid leukemia: Current advances and challenges
por: Chen, Ying, et al.
Publicado: (2023)

Podoplanin: Its roles and functions in neurological diseases and brain cancers
por: Wang, Yi, et al.
Publicado: (2022)

Honokiol Induces Ferroptosis by Upregulating HMOX1 in Acute Myeloid Leukemia Cells
por: Lai, Xingrong, et al.
Publicado: (2022)

Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation
por: Wu, Xue-Fei, et al.
Publicado: (2021)

Corrigendum: Scorpion Venom Heat-Resistant Peptide Attenuates Microglia Activation and Neuroinflammation
por: Wu, Xue-Fei, et al.
Publicado: (2021)

Vincristine-Induced Peripheral Neuropathy in Childhood Acute Lymphoblastic Leukemia: Genetic Variation as a Potential Risk Factor
por: Yang, Qing-Yan, et al.
Publicado: (2021)

Identification of Nanog as a novel inhibitor of Rad51
por: Xin, Ying, et al.
Publicado: (2022)

Low-frequency ultrasound irradiation increases paclitaxel-induced sarcoma cells apoptosis and facilitates the transmembrane delivery of drugs
por: Yang, Tana, et al.
Publicado: (2022)

Dax1 and Nanog act in parallel to stabilize mouse embryonic stem cells and induced pluripotency
por: Zhang, Junlei, et al.
Publicado: (2014)

YY1-induced upregulation of LncRNA-ARAP1-AS2 and ARAP1 promotes diabetic kidney fibrosis via aberrant glycolysis associated with EGFR/PKM2/HIF-1α pathway
por: Li, Xin, et al.
Publicado: (2023)

Population Pharmacokinetics of Polymyxin B and Dosage Optimization in Renal Transplant Patients
por: Li, Ying, et al.
Publicado: (2021)

Net Clinical Benefit of Non-vitamin K Antagonist Oral Anticoagulants for Venous Thromboembolism Prophylaxis in Patients With Cancer: A Systematic Review and Trade-Off Analysis From 9 Randomized Controlled Trials
por: Yan, Yi-Dan, et al.
Publicado: (2018)

Metabolic Activation of the Toxic Natural Products From Herbal and Dietary Supplements Leading to Toxicities
por: Wang, Yi-Kun, et al.
Publicado: (2021)

Nuciferine downregulates Per-Arnt-Sim kinase expression during its alleviation of lipogenesis and inflammation on oleic acid-induced hepatic steatosis in HepG(2) cells
por: Zhang, Dan-Dan, et al.
Publicado: (2015)

Context-Dependent Functions of NANOG Phosphorylation in Pluripotency and Reprogramming
por: Saunders, Arven, et al.
Publicado: (2017)

Dacomitinib for Advanced Non-small Cell Lung Cancer Patients Harboring Major Uncommon EGFR Alterations: A Dual-Center, Single-Arm, Ambispective Cohort Study in China
por: Li, Hong-Shuai, et al.
Publicado: (2022)

The Curcumin Analogs 2-Pyridyl Cyclohexanone Induce Apoptosis via Inhibition of the JAK2–STAT3 Pathway in Human Esophageal Squamous Cell Carcinoma Cells
por: Wang, Ying, et al.
Publicado: (2018)

Lower-dose corticosteroid therapy in severe immune thrombocytopenia during pregnancy: The comparable efficacy and lower incidence of maternal complications
por: Xu, Xue, et al.
Publicado: (2022)

Sagacious confucius’ pillow elixir ameliorates Dgalactose induced cognitive injury in mice via estrogenic effects and synaptic plasticity
por: Zhao, De-Ping, et al.
Publicado: (2022)

Drug-loaded PEG-PLGA nanoparticles for cancer treatment
por: Zhang, Dan, et al.
Publicado: (2022)

Protective effect of quercetin on pig intestinal integrity after transport stress is associated with regulation oxidative status and inflammation
por: ZOU, Yi, et al.
Publicado: (2016)

Dexmedetomidine Improves Postoperative Patient-Controlled Analgesia following Radical Mastectomy
por: Fan, Wei, et al.
Publicado: (2017)

Investigation of Liver Injury of Polygonum multiflorum Thunb. in Rats by Metabolomics and Traditional Approaches
por: Li, Yun-Xia, et al.
Publicado: (2017)

CNST is Characteristic of Leukemia Stem Cells and is Associated With Poor Prognosis in AML
por: Liu, Haoyu, et al.
Publicado: (2022)

Effect of Eurycoma longifolia Stem Extract on Uric Acid Excretion in Hyperuricemia Mice
por: Bao, Ruixia, et al.
Publicado: (2019)

Natural Products Against Renal Fibrosis via Modulation of SUMOylation
por: Liu, Peng, et al.
Publicado: (2022)

Comparative Pharmacokinetics of Gallic Acid After Oral Administration of Gallic Acid Monohydrate in Normal and Isoproterenol-Induced Myocardial Infarcted Rats
por: Yu, Zhe, et al.
Publicado: (2018)

Krüppel-like factor 4 induces apoptosis and inhibits tumorigenic progression in SK-BR-3 breast cancer cells
por: Wang, Bing, et al.
Publicado: (2015)

Effect of traditional Chinese medicine on postoperative depression of breast cancer: a systematic review and meta-analysis
por: Wang, Yan, et al.
Publicado: (2023)

Nanog mediated by FAO/ACLY signaling induces cellular dormancy in colorectal cancer cells
por: Zhang, Meng, et al.
Publicado: (2022)

High-Throughput and Untargeted Metabolic Profiling Revealed the Potential Effect and Mechanisms of Paeoniflorin in Young Asthmatic Rats
por: Wang, Dan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u88fcvtl8qe22q9q112de52q2j