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Recombinant Lipoprotein Rv1016c Derived from Mycobacterium tuberculosis Is a TLR-2 Ligand that Induces Macrophages Apoptosis and Inhibits MHC II Antigen Processing

TLR2-dependent cellular signaling in Mycobacterium tuberculosis-infected macrophages causes apoptosis and inhibits class II major histocompatibility complex (MHC-II) molecules antigen processing, leading to evasion of surveillance. Mycobacterium tuberculosis (MTB) lipoproteins are an important class...

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Detalles Bibliográficos
Autores principales:	Su, Haibo, Zhu, Shenglin, Zhu, Lin, Huang, Wei, Wang, Honghai, Zhang, Zhi, Xu, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114242/ https://www.ncbi.nlm.nih.gov/pubmed/27917375 http://dx.doi.org/10.3389/fcimb.2016.00147

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