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Nuclear Localization of Suppressor of Cytokine Signaling-1 Regulates Local Immunity in the Lung

Suppressor of cytokine signaling 1 (SOCS1) is a negative feedback inhibitor of cytoplasmic Janus kinase and signal transducer and activator of transcription (STAT) signaling. SOCS1 also contains a nuclear localization sequence (NLS), yet, the in vivo importance of nuclear translocation is unknown. W...

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Detalles Bibliográficos
Autores principales:	Zimmer, Jana, Weitnauer, Michael, Boutin, Sébastien, Küblbeck, Günter, Thiele, Sabrina, Walker, Patrick, Lasitschka, Felix, Lunding, Lars, Orinska, Zane, Vock, Christina, Arnold, Bernd, Wegmann, Michael, Dalpke, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114302/ https://www.ncbi.nlm.nih.gov/pubmed/27917175 http://dx.doi.org/10.3389/fimmu.2016.00514

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