The Role of PDGFR-β Activation in Acquired Resistance to IGF-1R Blockade in Preclinical Models of Rhabdomyosarcoma()

To determine what alternative pathways may act as mechanisms of bypass resistance to type 1 insulin-like growth factor receptor (IGF-1R) blockade in rhabdomyosarcoma (RMS), we compared expression of receptor tyrosine kinase activity in a number of IGF-1R antibody-resistant and -sensitive RMS cell li...

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Detalles Bibliográficos
Autores principales: Heske, Christine M., Yeung, Choh, Mendoza, Arnulfo, Baumgart, Joshua T., Edessa, Leah D., Wan, Xiaolin, Helman, Lee J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2016
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114528/
https://www.ncbi.nlm.nih.gov/pubmed/27835791
http://dx.doi.org/10.1016/j.tranon.2016.09.002

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