Notch regulates BMP responsiveness and lateral branching in vessel networks via SMAD6

Functional blood vessel growth depends on generation of distinct but coordinated responses from endothelial cells. Bone morphogenetic proteins (BMP), part of the TGFβ superfamily, bind receptors to induce phosphorylation and nuclear translocation of SMAD transcription factors (R-SMAD1/5/8) and regul...

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Detalles Bibliográficos
Autores principales: Mouillesseaux, Kevin P., Wiley, David S., Saunders, Lauren M., Wylie, Lyndsay A., Kushner, Erich J., Chong, Diana C., Citrin, Kathryn M., Barber, Andrew T., Park, Youngsook, Kim, Jun-Dae, Samsa, Leigh Ann, Kim, Jongmin, Liu, Jiandong, Jin, Suk-Won, Bautch, Victoria L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114582/
https://www.ncbi.nlm.nih.gov/pubmed/27834400
http://dx.doi.org/10.1038/ncomms13247

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