Unlocking the chromatin code by deciphering protein–DNA interactions

Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation. In their recent study, Krijgsveld and colleagues (Rafiee et al, 2016) report ChIP‐SICAP, a powerful tool for deciphering the chr...

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Detalles Bibliográficos
Autores principales: Bensaddek, Dalila, Lamond, Angus I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
News & Views
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114617/
https://www.ncbi.nlm.nih.gov/pubmed/27837035
http://dx.doi.org/10.15252/msb.20167332
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author Bensaddek, Dalila
Lamond, Angus I
author_facet Bensaddek, Dalila
Lamond, Angus I
author_sort Bensaddek, Dalila
collection PubMed
description Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation. In their recent study, Krijgsveld and colleagues (Rafiee et al, 2016) report ChIP‐SICAP, a powerful tool for deciphering the chromatin proteome by combining chromatin immunoprecipitation, selective isolation of chromatin‐associated proteins and mass spectrometry.
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spelling pubmed-51146172016-11-25 Unlocking the chromatin code by deciphering protein–DNA interactions Bensaddek, Dalila Lamond, Angus I Mol Syst Biol News & Views Characterizing the composition of protein complexes bound to different genomic loci is essential for advancing our mechanistic understanding of transcriptional regulation. In their recent study, Krijgsveld and colleagues (Rafiee et al, 2016) report ChIP‐SICAP, a powerful tool for deciphering the chromatin proteome by combining chromatin immunoprecipitation, selective isolation of chromatin‐associated proteins and mass spectrometry. John Wiley and Sons Inc. 2016-11-11 /pmc/articles/PMC5114617/ /pubmed/27837035 http://dx.doi.org/10.15252/msb.20167332 Text en © 2016 The Authors. Published under the terms of the CC BY 4.0 license This is an open access article under the terms of the Creative Commons Attribution 4.0 (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle News & Views
Bensaddek, Dalila
Lamond, Angus I
Unlocking the chromatin code by deciphering protein–DNA interactions
title Unlocking the chromatin code by deciphering protein–DNA interactions
title_full Unlocking the chromatin code by deciphering protein–DNA interactions
title_fullStr Unlocking the chromatin code by deciphering protein–DNA interactions
title_full_unstemmed Unlocking the chromatin code by deciphering protein–DNA interactions
title_short Unlocking the chromatin code by deciphering protein–DNA interactions
title_sort unlocking the chromatin code by deciphering protein–dna interactions
topic News & Views
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114617/
https://www.ncbi.nlm.nih.gov/pubmed/27837035
http://dx.doi.org/10.15252/msb.20167332
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