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tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence
Microbial pathogens adapt to the stress of infection by regulating transcription, translation and protein modification. We report that changes in gene expression in hypoxia-induced non-replicating persistence in mycobacteria—which models tuberculous granulomas—are partly determined by a mechanism of...
Autores principales: | Chionh, Yok Hian, McBee, Megan, Babu, I. Ramesh, Hia, Fabian, Lin, Wenwei, Zhao, Wei, Cao, Jianshu, Dziergowska, Agnieszka, Malkiewicz, Andrzej, Begley, Thomas J., Alonso, Sylvie, Dedon, Peter C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114619/ https://www.ncbi.nlm.nih.gov/pubmed/27834374 http://dx.doi.org/10.1038/ncomms13302 |
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