Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

BACKGROUND: Tumor-infiltrating immune cells have been linked to prognosis and response to immunotherapy; however, the levels of distinct immune cell subsets and the signals that draw them into a tumor, such as the expression of antigen presenting machinery genes, remain poorly characterized. Here, w...

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Detalles Bibliográficos
Autores principales: Şenbabaoğlu, Yasin, Gejman, Ron S., Winer, Andrew G., Liu, Ming, Van Allen, Eliezer M., de Velasco, Guillermo, Miao, Diana, Ostrovnaya, Irina, Drill, Esther, Luna, Augustin, Weinhold, Nils, Lee, William, Manley, Brandon J., Khalil, Danny N., Kaffenberger, Samuel D., Chen, Yingbei, Danilova, Ludmila, Voss, Martin H., Coleman, Jonathan A., Russo, Paul, Reuter, Victor E., Chan, Timothy A., Cheng, Emily H., Scheinberg, David A., Li, Ming O., Choueiri, Toni K., Hsieh, James J., Sander, Chris, Hakimi, A. Ari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5114739/
https://www.ncbi.nlm.nih.gov/pubmed/27855702
http://dx.doi.org/10.1186/s13059-016-1092-z

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