Saline Infusion and Amiloride in the Management of Lithium Toxicity

This paper describes the case of a 74 year old patient who became lithium toxic after 15 years of lithium therapy. We discuss the clinical presentation of the case and some of the possible causes of the sudden development of his toxicity. Although haemodialysis is the treatment of choice for severe...

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Detalles Bibliográficos
Autores principales: Czerniewski, Ian W D, Short, Jacquline A, McConnell, A A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Clinical Press 1990
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115052/
https://www.ncbi.nlm.nih.gov/pubmed/2093357
Descripción
Sumario:This paper describes the case of a 74 year old patient who became lithium toxic after 15 years of lithium therapy. We discuss the clinical presentation of the case and some of the possible causes of the sudden development of his toxicity. Although haemodialysis is the treatment of choice for severe lithium toxicity it is not always available. In this paper we propose that the combination of saline diuresis and Amiloride may provide a suitable alternative in the management of lithium toxicity.

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