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Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea
OBJECTIVES: Previous studies examining the association between osteoporosis (OP) and hearing loss (HL) have shown conflicting results. The objective of the present study was to examine the association between hearing impairment and OP in postmenopausal women, using appropriate statistical analyses....
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Otorhinolaryngology-Head and Neck Surgery
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115157/ https://www.ncbi.nlm.nih.gov/pubmed/27136368 http://dx.doi.org/10.21053/ceo.2015.01858 |
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author | Jung, Da Jung Cho, Hyun Ho Lee, Kyu-Yup |
author_facet | Jung, Da Jung Cho, Hyun Ho Lee, Kyu-Yup |
author_sort | Jung, Da Jung |
collection | PubMed |
description | OBJECTIVES: Previous studies examining the association between osteoporosis (OP) and hearing loss (HL) have shown conflicting results. The objective of the present study was to examine the association between hearing impairment and OP in postmenopausal women, using appropriate statistical analyses. METHODS: Total 1,009 participants were included in the current study. The propensity score matched (PSM) cohort was defined as the cohort including participants diagnosed with OP and participants without OP. Three statistical models were developed where model 1 was unadjusted, model 2 included age, and model 3 included age, body mass index, alcohol intake, smoking habit, diabetes mellitus, hypertension, high density lipoprotein cholesterol, triglyceride level, vitamin D, and alkaline phosphatase. RESULTS: There were 776 and 233 participants in the groups diagnosed without and with OP, respectively. For propensity score matching, 233 pairs were selected from the 776 participants without OP. In the total cohort, using statistical models 2 and 3, no significant difference in the four hearing thresholds was identified between the 2 groups. Logistic regression indicated that, in model 3, participants with OP had a 1.128 (P=0.323) increased risk HL. A significant HL risk was not observed in participants with OP. Using statistical model 3, there were no significant associations among lumbar spine or femoral neck T-scores and changes in the hearing thresholds. In the PSM cohort, statistical models also showed similar results. CONCLUSION: The current study did not demonstrate and association between bone mineral density and hearing impairment in the study population of postmenopausal Korean women. |
format | Online Article Text |
id | pubmed-5115157 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Korean Society of Otorhinolaryngology-Head and Neck Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-51151572016-12-01 Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea Jung, Da Jung Cho, Hyun Ho Lee, Kyu-Yup Clin Exp Otorhinolaryngol Original Article OBJECTIVES: Previous studies examining the association between osteoporosis (OP) and hearing loss (HL) have shown conflicting results. The objective of the present study was to examine the association between hearing impairment and OP in postmenopausal women, using appropriate statistical analyses. METHODS: Total 1,009 participants were included in the current study. The propensity score matched (PSM) cohort was defined as the cohort including participants diagnosed with OP and participants without OP. Three statistical models were developed where model 1 was unadjusted, model 2 included age, and model 3 included age, body mass index, alcohol intake, smoking habit, diabetes mellitus, hypertension, high density lipoprotein cholesterol, triglyceride level, vitamin D, and alkaline phosphatase. RESULTS: There were 776 and 233 participants in the groups diagnosed without and with OP, respectively. For propensity score matching, 233 pairs were selected from the 776 participants without OP. In the total cohort, using statistical models 2 and 3, no significant difference in the four hearing thresholds was identified between the 2 groups. Logistic regression indicated that, in model 3, participants with OP had a 1.128 (P=0.323) increased risk HL. A significant HL risk was not observed in participants with OP. Using statistical model 3, there were no significant associations among lumbar spine or femoral neck T-scores and changes in the hearing thresholds. In the PSM cohort, statistical models also showed similar results. CONCLUSION: The current study did not demonstrate and association between bone mineral density and hearing impairment in the study population of postmenopausal Korean women. Korean Society of Otorhinolaryngology-Head and Neck Surgery 2016-12 2016-05-03 /pmc/articles/PMC5115157/ /pubmed/27136368 http://dx.doi.org/10.21053/ceo.2015.01858 Text en Copyright © 2016 by Korean Society of Otorhinolaryngology-Head and Neck Surgery This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Jung, Da Jung Cho, Hyun Ho Lee, Kyu-Yup Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea |
title | Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea |
title_full | Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea |
title_fullStr | Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea |
title_full_unstemmed | Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea |
title_short | Association of Bone Mineral Density With Hearing Impairment in Postmenopausal Women in Korea |
title_sort | association of bone mineral density with hearing impairment in postmenopausal women in korea |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115157/ https://www.ncbi.nlm.nih.gov/pubmed/27136368 http://dx.doi.org/10.21053/ceo.2015.01858 |
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