Dual function of MDM2 and MDMX toward the tumor suppressors p53 and RB

The orchestrated crosstalk between the retinoblastoma (RB) and p53 pathways contributes to preserving proper homeostasis within the cell. The deregulation of one or both pathways is a common factor in the development of most types of human cancer. The proto-oncoproteins MDMX and MDM2 are the main re...

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Detalles Bibliográficos
Autores principales: Hernández-Monge, Jesús, Rousset-Roman, Adriana Berenice, Medina-Medina, Ixaura, Olivares-Illana, Vanesa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115168/
https://www.ncbi.nlm.nih.gov/pubmed/28050229
http://dx.doi.org/10.18632/genesandcancer.120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115168/
https://www.ncbi.nlm.nih.gov/pubmed/28050229
http://dx.doi.org/10.18632/genesandcancer.120

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