MIDA boronates are hydrolysed fast and slow by two different mechanisms

MIDA boronates (N-methylimidodiacetic boronic acid esters) serve as an increasingly general platform for building-block-based small molecule construction, largely due to the dramatic and general rate differences with which they are hydrolysed under various basic conditions. Yet the mechanistic under...

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Detalles Bibliográficos
Autores principales: Gonzalez, Jorge A., Ogba, O. Maduka, Morehouse, Gregory F., Rosson, Nicholas, Houk, Kendall N., Leach, Andrew G., Cheong, Paul H.-Y., Burke, Martin D., Lloyd-Jones, Guy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115273/
https://www.ncbi.nlm.nih.gov/pubmed/27768100
http://dx.doi.org/10.1038/nchem.2571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115273/
https://www.ncbi.nlm.nih.gov/pubmed/27768100
http://dx.doi.org/10.1038/nchem.2571

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