Nanochannel Electroporation as a Platform for Living Cell Interrogation in Acute Myeloid Leukemia

A living cell interrogation platform based on nanochannel electroporation is demonstrated with analysis of RNAs in single cells. This minimally invasive process is based on individual cells and allows both multi‐target analysis and stimulus‐response analysis by sequential deliveries. The unique plat...

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Detalles Bibliográficos
Autores principales: Zhao, Xi, Huang, Xiaomeng, Wang, Xinmei, Wu, Yun, Eisfeld, Ann‐Kathrin, Schwind, Sebastian, Gallego‐Perez, Daniel, Boukany, Pouyan E., Marcucci, Guido I., Lee, Ly James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115302/
https://www.ncbi.nlm.nih.gov/pubmed/27980918
http://dx.doi.org/10.1002/advs.201500111
Descripción
Sumario:A living cell interrogation platform based on nanochannel electroporation is demonstrated with analysis of RNAs in single cells. This minimally invasive process is based on individual cells and allows both multi‐target analysis and stimulus‐response analysis by sequential deliveries. The unique platform possesses a great potential to the comprehensive and lysis‐free nucleic acid analysis on rare or hard‐to‐transfect cells. [Image: see text]

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